3DO 	Opera
Amiga 	PUAE_libretro (based on WinUAE)
Apple II 	Virtu
Arcade 	MAME
Atari 2600 	Original, Stella
Atari 7800 	Original
Atari Jaguar + CD 	Virtual Jaguar
Atari Lynx 	Mednafen's Handy core
Bandai WonderSwan/Color 	Mednafen's Cygne core
ColecoVision 	Original
Commodore 64 	Original
DOOM/Heretic/Hexen 	DSDA-Doom
Fairchild Channel F 	Original
GCE Vectrex 	Original
Magnavox Odyssey² 	Original
Mattel Intellivision 	Original
MS-DOS/Win9x 	DOSBox-X
MSX 	Original
NEC PC Engine (TurboGrafx-16) and SuperGrafx + CD 	Original (PCEHawk (to be dropped eventually)), Mednafen (TurboNyma, HyperNyma)
NEC PC-FX 	Mednafen (T.S.T.)
Nintendo 3DS 	Encore (fork of Citra)
Nintendo 64 + 64DD 	Mupen64Plus (v2.0, for N64, in the process of update to v2.6), ares (for 64DD)
Nintendo DS/DSi 	melonDS
Nintendo Entertainment System/Famicom + Famicom Disk System 	Original (PPU based on FCEUX), quickerNES.
Nintendo Game Boy Advance 	mGBA
Nintendo Virtual Boy 	Mednafen (Virtual Boyee)
Sega Genesis/Mega Drive, Sega/Mega CD, Sega Pico 	Genesis Plus GX
Sega 32X 	PicoDrive
Sega Saturn 	Mednafen (Saturnus)
Sega SG-1000, Master System, Game Gear 	Original
Sinclair ZX Spectrum 	Original
Sony PlayStation 	Mednafen (Octoshock (to be dropped eventually), Nymashock)
SNK Neo Geo Pocket/Color 	Mednafen's NeoPop core
Super Nintendo Entertainment System/Super Famicom + Satellaview 	bsnes (v087 (to be dropped eventually), v115+), Snes9x (1.54), Mednafen (SNES-Faust)
Super Game Boy/Game Boy/Game Boy Color 	Original, Gambatte, bsnes (v087 (to be dropped eventually), v115+), SameBoy
TI-83 	Original (to be dropped eventually), Emu83
TIC-80 	Ported
Uzebox 	Uzem